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The PAPP-A test is one of the prenatal tests that plays an important role in assessing the risk of genetic defects in the developing fetus.In this article, we will discuss what exactly the PAPP-A test is, who should perform it, how to interpret the results, how much it costs and whether it is reimbursed.
Papp-a test – what is it?
The abbreviation PAPP-A stands for “Pregnancy-Associated Plasma Protein-A” and it is a protein produced by the placenta during pregnancy.The PAPP-A test measures the level of this protein in the mother’s blood.This test is often performed in combination with another test, such as the nuchal impression test (NT), creating the so-calledcombined test.
During the PAPP-A test, a doctor or nurse takes a blood sample from the expectant mother.They then analyze the level of PAPP-A in this sample.The result is expressed in units of momole per liter (U/L).PAPP-A values may vary depending on maternal age and other factors, so it is important that the results are interpreted by a specialist.
Papp-a test – who should perform it?
PAPP-A testing is recommended primarily to future mothers who are at increased risk of genetic defects in the fetus.These are among others:
- Women over the age of 35, because the risk of genetic defects increases with the mother’s age.
- Women who have a history of genetic abnormalities in their family.
- Women who received results from other prenatal tests suggesting an increased risk.
However, it is worth remembering that each pregnancy is different, so the decision to perform the PAPP-A test should be made by the future mother in consultation with her doctor.
Papp-a test – standards.interpretation of double test results
Interpretation of the PAPP-A test results is usually part of the so-calleddouble test, which also includes measurement of the uterine nuchal impression (NT).The final assessment of the risk of genetic defects is based on the analysis of the results of both these tests and additional factors, such as the mother’s age and family history.
If the PAPP-A test result is lower than expected, it may indicate an increased risk of genetic defects in the fetus.However, this is not the only factor taken into account in a risk assessment, so it is important that the results are interpreted by a specialist.After careful analysis, your doctor may recommend further diagnostic tests, such as amniocentesis or chorionic villus sampling.
Papp-a test – price and reimbursement
The price of the PAPP-A test may vary and depends on the place where the test is performed and its type (e.g. whether it is a private test or financed by the health care system).In Poland, the prices of this test range from several hundred to several thousand zlotys.
It is worth noting that in some cases the PAPP-A test may be reimbursed by the National Health Fund (NFZ), if there are appropriate medical indications.It is worth seeking information from the doctor supervising the pregnancy to find out whether you can benefit from a refund.
Your suggestions
If you are planning a pregnancy or are already pregnant, it is always worth consulting your doctor about prenatal testing and assessing the risk of genetic defects in the fetus.This will allow you to make the best decisions regarding maternal and child health care.
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