Antihistamines – action and side effects

Histamine is one of the key chemical mediators in the human body, playing an important role in allergic reactions and the regulation of many physiological processes. Its excessive activation may lead to various ailments, such as a runny nose, itching, hives or swelling. Antihistamines are used to relieve these symptoms, but their effects and side effects are worth knowing in detail.

What is histamine?

The history of histamine in the bodies of animals and humans goes back many years. It is an organic chemical compound that acts as a mediator in immune and allergic reactions. In the body, histamine can be released as a result of various stimuli, such as contact with an allergen, injuries or infections. Its action mainly involves dilating blood vessels, increasing vascular permeability and contracting smooth muscles, which leads to characteristic allergy symptoms.

How do antihistamines work?

Antihistamines, also called antihistamines, are pharmacological substances that affect histamine receptors in the body. There are three main classes of antihistamines: first, second and third generation. Each of these classes has its own properties and uses.

Antihistamines – indications

Antihistamines are widely used in medicine. They are mainly used to relieve allergy symptoms such as runny nose, sneezing, itchy skin, hives or swelling. In addition, they can also be used to treat some dermatological diseases, as well as to alleviate the symptoms of autoimmune diseases.

Antihistamines – classification

As already mentioned, there are three main classes of antihistamines: first, second and third generation. First-generation drugs such as diphenhydramine tend to cause drowsiness and are less selective in their action on histamine receptors. Second-generation drugs, such as loratadine, are less sedative and have a longer duration of action. However, third-generation drugs, such as desloratadine, have an even lower risk of drowsiness and are more selective in their action.

Antihistamines – contraindications and side effects

Unfortunately, like any drug, antihistamines may cause side effects and have their contraindications. The most common side effect is drowsiness, especially when using first-generation drugs. There may also be problems with the digestive system, dry mouth, headaches and dizziness.

Your suggestions

If you’re wondering whether antihistamines are right for you, it’s always worth checking with your doctor. A specialist can assess your situation and recommend appropriate therapy, taking into account the potential benefits and the risk of side effects.

Recommended articles

If you want to learn more about antihistamines, their uses and side effects, it is worth reaching for additional sources of information. Below are some recommended articles on this topic:

“Antihistamines – what types are they and when is it worth using them” – available on the XYZ medical portal.

“Side effects of antihistamines – what is worth knowing” – an article on the website of specialist XYZ.

“Histamine and allergies – how it works and why it is worth using antihistamines” – publication in the ABC medical journal.

By having access to these articles, you will be more aware of the effects of antihistamines and can make better decisions about your health.