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Biologics, also known as monoclonal antibody biologics, are an innovative class of drugs used to treat a variety of autoimmune diseases, including atopic dermatitis (AD) and psoriasis. In this article, we will take a closer look at this fascinating issue, understand how biological drugs work, their types and effectiveness in treating these diseases, and discuss issues related to costs, reimbursement, side effects and the impact on fertility and alcohol consumption.
Biological drugs – what are they? what are their types?
Biological drugs are special proteins or antibodies that are produced using biotechnology. They are designed to target specific disease factors in the body. There are several types of biological drugs, but the most commonly used are monoclonal antibodies, which have the ability to inhibit inflammatory processes and regulate the immune system.
Biological drugs – action
The mechanism of action of biologics is that they block specific cytokines or other molecules that play a key role in inflammatory and autoimmune processes. Thanks to this, they reduce the symptoms of the disease and improve the patient’s quality of life.
Division of biological drugs
Biological drugs can be divided into several categories, depending on their therapeutic purpose. In the case of atopic dermatitis and psoriasis, the most commonly used biological drugs are monoclonal antibodies that act on interleukin 4 (IL-4) and interleukin 13 (IL-13), such as dupilumab. There are also drugs that target interleukin 17 (IL-17), such as secukinumab.
How much does biological drug therapy cost?
Biologics are typically more expensive than traditional pain medications. The costs of therapy may vary depending on the type of drug, dose and duration of therapy. However, biologic therapy can be significantly expensive, which may pose a challenge for some patients.
Are biological drugs reimbursed by the national health fund?
Yes, biological drugs are reimbursed by the National Health Fund (NFZ) in Poland. However, there are specific eligibility criteria that a patient must meet to receive reimbursement. Patients with atopic dermatitis and psoriasis are usually granted financial resources for therapy with biological drugs if they do not improve after treatment with traditional methods.
Efficacy of biological drug therapy
The effectiveness of biologic drug therapy in atopic dermatitis and psoriasis is well documented. Clinical trials have shown that these drugs can significantly improve patients’ condition by reducing itching, redness and peeling of the skin. The effects of therapy may vary from patient to patient, but for many they provide significant relief.
Biological drugs and fertility
Currently, there is insufficient scientific data on the effects of biologics on fertility. However, patients planning a pregnancy should consult their doctor before starting therapy to discuss the potential risks and benefits.
Biological drugs and alcohol
Most studies do not show a direct negative effect of biologics on alcohol consumption. However, you should always consult your doctor and follow diet and lifestyle recommendations during therapy.
Biological drug therapy – side effects
Like any medicine, biologics may cause side effects. The most common of them are skin reactions at the site of drug administration, headaches, weakness and the risk of infection. Nevertheless, most patients tolerate the therapy well and the benefits outweigh the risk of side effects.
Examples of names of biological drugs in poland
Various biological drugs are available in Poland for the treatment of atopic dermatitis and psoriasis. Some of them are:
- Dupilumab (trade name: Dupixent)
- Secukinumab (trade name: Cosentyx)
Your suggestions
If you have questions about biologic therapy or would like more information on this topic, please consult your doctor or dermatologist. Each patient is different, so an individual approach to treatment is key.
Recommended articles
If you want to learn more about biologics, it is also worth reading scientific articles and medical guides on this topic. You can also consult with patients who have undergone biologic therapy to learn more about their experiences and results.
It is worth remembering that biological drugs represent a breakthrough in the treatment of chronic skin diseases and allergies, offering hope for improving the quality of life of patients and controlling the symptoms of the disease.