Methylated folic acid – should women without mthfr mutations supplement it?

Nowadays, a healthy lifestyle and proper diet are a priority, especially for pregnant women and those planning motherhood. One of the important components of the diet is folic acid, also known as vitamin B9. However, we hear more and more often about methylated folic acid and its benefits. How does it differ from standard folate and should all women supplement it?

Methylated folic acid and folate – what is the difference?

Before we discuss methylated folic acid, it is worth understanding how it differs from traditional folate. Folic acid is a synthetic form of vitamin B9, commonly used as a dietary supplement and an ingredient of many food products. However, not every body is able to effectively process folic acid in its standard form.

Methylated folic acid, also called 5-MTHF (5-methyl-tetrahydrofolate), is a more advanced and natural form of vitamin B9. It is already a ready-made form that the body can easily absorb. It works faster and more effectively than traditional folic acid, which is why it is increasingly recommended, especially to pregnant women and women planning motherhood.

Methylated folic acid and mthfr gene mutation

Now that we understand the difference between folic acid and methylated folate, it is worth mentioning the role of MTHFR (methylenetetrahydrofolate reductase) gene mutations in folate processing. A mutation in this gene may affect the body’s ability to convert folic acid into its active form.

People with an MTHFR gene mutation may have difficulty absorbing standard folic acid, which may lead to vitamin B9 deficiency. For them, supplementation with methylated folic acid may be particularly beneficial because it is a ready-made form that the body can use directly. Research suggests that women with an MTHFR mutation may have an increased risk of pregnancy complications, so it is worth consulting a doctor and considering supplementation.

Methylated folic acid – how to dose during and before pregnancy

Once we decide to supplement with methylated folic acid, it is important to determine the appropriate dose. For pregnant women and those planning motherhood, it is recommended to take 400-800 micrograms (mcg) of 5-MTHF per day. However, the exact dosage may vary depending on individual needs and medical recommendations.

Please remember that methylated folic acid is not a substitute for a healthy diet, but a supplement. It’s important to also eat foods rich in natural sources of vitamin B9, such as spinach leaves, broccoli, avocado and beans.

Methylated folic acid – what not to combine with?

When supplementing with methylated folic acid, it is also worth paying attention to what it should not be combined with. There are certain substances and medications that may affect the absorption of 5-MTHF. The simultaneous use of methotrexate, antiepileptic drugs, trimethoprim antibiotics and large amounts of alcohol should be avoided because they may interfere with the absorption of this form of folic acid.

Your suggestions

Each body is different, so before starting supplementation with methylated folic acid, it is worth consulting a doctor or nutrition specialist. Your doctor can perform appropriate genetic testing to see if you have an MTHFR gene mutation and whether supplementation is beneficial to you.

Recommended articles

If you are interested in the topic of methylated folic acid and its impact on health, it is worth reading more about it. Below you will find some recommended articles that can expand your knowledge on this topic:

1. “The role of folic acid in fetal development”
2. “Folic acid and heart health”
3. “The impact of folic acid on mental health”

To sum up, methylated folic acid may be a valuable addition to the diet of pregnant women and those planning motherhood, especially in the case of MTHFR gene mutations. However, it is always worth consulting your doctor and adjusting the dose of the supplement to your individual needs. A healthy diet and appropriate eating habits remain crucial for the healthy development of the fetus and maintaining good body condition.