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Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used painkillers and anti-inflammatory drugs.
In this article, we will discuss their mechanism of action, use, reasons for the increase in side effects, general principles of use, and share suggestions and recommended articles for those who want to learn more.
Mechanism of action
NSAIDs work by inhibiting an enzyme called cyclooxygenase (COX). COX is responsible for the production of prostaglandins, which are chemicals involved in inflammation and pain processes in the body. Blocking COX by NSAIDs reduces the production of prostaglandins, which translates into reduced inflammation and pain relief.
There are different types of NSAIDs, including over-the-counter medications such as ibuprofen and aspirin, and those that require a prescription, such as naproxen and diclofenac. Each of these drugs has a slightly different mechanism of action and half-life, which affects their effectiveness and side effects.
Application
NSAIDs are widely used in medicine. They are used to treat pain of various origins, including rheumatic pain, muscle pain, postoperative pain and pain associated with arthritis. In addition, NSAIDs are often used in the treatment of inflammatory diseases such as arthritis, systemic lupus erythematosus and enteritis.
However, it is worth remembering that NSAIDs are not suitable for every person. People with stomach diseases, asthma, hypertension or blood clotting disorders should consult a doctor before starting NSAID therapy, because these drugs may have side effects and interactions with other drugs.
Reasons for the increase in side effects
Although NSAIDs are effective drugs, they are unfortunately often associated with side effects. One of the main reasons is the effect these drugs have on the digestive system. NSAIDs can cause damage to the stomach lining, which may lead to ulceration and bleeding. They also affect the kidneys, which may cause problems with their functioning.
Another factor influencing side effects is the long-term use of NSAIDs in high doses. The longer you take medications, the greater the risk of side effects.
General rules for using NSAIDs
To minimize the risk of side effects when using NSAIDs, it is worth following a few general rules:
- Do not exceed the recommended dose of the drug.
- Do not use NSAIDs on an empty stomach to minimize gastric irritation.
- Monitor your well-being regularly and inform your doctor about any side effects.
- Consult your doctor before starting therapy, especially if you have other medical conditions or are taking other medications.
Your suggestions
If you need treatment for pain or inflammation and are considering using NSAIDs, it is always worth consulting your doctor. He will be able to assess your needs and tailor appropriate therapy. Remember that self-medication with NSAIDs can lead to serious side effects.
Recommended articles
If you want to learn more about nonsteroidal anti-inflammatory drugs, we recommend reading the following articles:
- “NSAIDs and stomach diseases: how to minimize the risk” – an article discussing the impact of NSAIDs on the digestive system and ways to protect it.
- “NSAIDs in the treatment of rheumatic diseases” – an article focusing on the applications of NSAIDs in the treatment of musculoskeletal diseases.
- “Safety of using NSAIDs in children and the elderly” – information on the use of NSAIDs in various age groups.
Remember that knowledge about nonsteroidal anti-inflammatory drugs is crucial for their safe and effective use. It’s always important to be well-informed to make informed decisions about your health.