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Immunoglobulin E, or IgE, is one of the key components of our immune system, playing a role in defending the body against various allergic substances.
Testing the total IgE level can be helpful in diagnosing and monitoring various allergic diseases. In this article, we will discuss what IgE is, when and why it is worth testing its level, what the norms are in children and adults, and what are the potential consequences of high results.
Immunoglobulin E, or IgE, is one of the five main types of antibodies in the human body. Its main role is to cause allergic reactions in response to foreign substances, such as pollen, animal hair, food or environmental allergens. IgE testing may be indicated when allergies or asthma are suspected, or when a patient experiences symptoms such as a runny nose, itching, difficulty breathing or skin rash.
It is worth noting that the IgE level test may include both total IgE and specific IgE. Total IgE is the total amount of immunoglobulin E in the body, while specific IgE is the amount of this immunoglobulin that is associated with a specific allergen. Specific IgE testing is more precise and helps identify which substances the patient’s body reacts allergic to. However, the total IgE test provides a general picture of the activity of the immune system in response to various allergens.
Total IgE levels may vary depending on the laboratory that performs the test. Generally, however, in children and adults, normal values are considered to range from 0 to 100 IU/ml. It is worth noting that IgE levels may be elevated in some people without allergy symptoms, so the interpretation of the results should always be carefully analyzed by a specialist.
High levels of total IgE may indicate that the immune system is active in response to allergens or other irritants. They may also suggest the presence of allergies, asthma, atopic dermatitis or other immunological diseases. However, high IgE may also occur in other disease states, so it is important to consult the results with a doctor who will carefully assess the patient’s clinical situation.
Testing the level of total IgE and specific IgE is necessary in the process of diagnosing allergies. This allows doctors to identify the allergens to which the patient’s body reacts, enabling more effective allergy management and avoiding triggers. IgE testing can also be used to monitor the effectiveness of allergy therapies such as allergen immunotherapy.
Total IgE testing costs may vary by region and laboratory. In some cases, the test may be reimbursed by the health care system. To be tested, you usually need a referral from your doctor, who will assess the need for the test based on your symptoms and history.
If you suspect an allergy or experience allergic symptoms, it is worth consulting a doctor who may order appropriate tests, including measuring the level of total IgE and/or specific IgE. This will help identify allergens and tailor therapy to improve the patient’s quality of life.
Here are some recommended articles that may be useful in understanding the topic of immunoglobulin E (IgE) and allergies:
Remember that each case of allergy is unique, so an individual approach to diagnosis and treatment is important, always under the supervision of a qualified doctor.